Martin J van den Bent Selected Research

ceritinib

1/2022

ASCEND-7: Efficacy and Safety of Ceritinib Treatment in Patients with ALK-Positive Non-Small Cell Lung Cancer Metastatic to the Brain and/or Leptomeninges.

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Martin J van den Bent Research Topics

Disease

72	Glioma (Gliomas) 06/2024 - 12/2003
72	Neoplasms (Cancer) 04/2024 - 08/2003
63	Glioblastoma (Glioblastoma Multiforme) 10/2023 - 03/2005
19	Brain Neoplasms (Brain Tumor) 08/2023 - 08/2003
18	Oligodendroglioma 01/2020 - 03/2003
15	Astrocytoma (Pilocytic Astrocytoma) 03/2024 - 02/2005
8	Lymphoma (Lymphomas) 04/2024 - 10/2010
7	Epilepsy (Aura) 01/2023 - 08/2014
5	Disease Progression 08/2023 - 03/2003
5	Neoplasm Metastasis (Metastasis) 02/2023 - 01/2018
4	Fatigue 10/2023 - 08/2014
4	Necrosis 11/2019 - 05/2008
3	Meningioma (Meningiomas) 12/2023 - 12/2020
3	Seizures (Absence Seizure) 01/2023 - 01/2021
2	Residual Neoplasm 04/2024 - 11/2013
2	Central Nervous System Neoplasms 01/2022 - 05/2018
2	Infections 11/2016 - 08/2014
2	Thrombocytopenia (Thrombopenia) 09/2014 - 08/2014
1	Carcinogenesis 06/2024
1	Melanoma (Melanoma, Malignant) 02/2023
1	Drug Resistant Epilepsy 01/2023
1	Genomic Instability 01/2023
1	Ganglioglioma 12/2022
1	Mental Fatigue 12/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022
1	Circulating Neoplastic Cells 01/2022
1	Edema (Dropsy) 01/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2021
1	Respiratory Insufficiency (Respiratory Failure) 12/2021

Drug/Important Bio-Agent (IBA)

49	Temozolomide (Temodar)FDA LinkGeneric 03/2024 - 12/2003
27	Lomustine (CCNU)FDA Link 10/2022 - 02/2005
20	Vincristine (Oncovin)FDA LinkGeneric 10/2022 - 02/2005
19	Procarbazine (Matulane)FDA Link 10/2022 - 02/2005
15	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2024 - 11/2013
14	Biomarkers (Surrogate Marker)IBA 04/2024 - 06/2005
12	Bevacizumab (Avastin)FDA Link 01/2023 - 11/2007
7	Anticonvulsants (Antiepileptic Drugs)IBA 01/2023 - 09/2007
6	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 01/2015
6	ErbB Receptors (EGF Receptor)IBA 01/2020 - 02/2006
5	RNA (Ribonucleic Acid)IBA 03/2024 - 02/2016
5	Carmustine (FIVB)FDA Link 01/2024 - 06/2008
5	ParaffinIBA 01/2019 - 12/2009
5	Formaldehyde (Formol)FDA Link 01/2019 - 12/2009
5	Alkylating AgentsIBA 10/2012 - 05/2005
4	Methotrexate (Mexate)FDA LinkGeneric 01/2024 - 12/2017
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2023 - 09/2007
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2017 - 11/2007
3	vorasidenibIBA 12/2023 - 08/2023
3	Rituximab (Mabthera)FDA Link 12/2023 - 12/2017
3	EnzymesIBA 08/2023 - 01/2011
3	Levetiracetam (Keppra)FDA LinkGeneric 01/2023 - 01/2021
3	MethyltransferasesIBA 10/2016 - 02/2006
3	epidermal growth factor receptor VIIIIBA 07/2015 - 12/2007
2	SteroidsIBA 04/2024 - 11/2007
2	Amino Acids FDA Link 01/2024 - 12/2023
2	Teniposide (VM 26)FDA Link 01/2024 - 01/2019
2	Oxygen (Dioxygen)IBA 10/2023 - 10/2020
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2023 - 02/2006
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 12/2017
2	Angiogenesis InhibitorsIBA 01/2022 - 04/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 04/2010
2	Circulating Tumor DNAIBA 01/2022 - 01/2021
2	Contrast MediaIBA 12/2021 - 05/2018
2	GadoliniumIBA 12/2021 - 09/2010
2	depatuxizumab mafodotinIBA 01/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 03/2020 - 08/2003
2	Monoclonal AntibodiesIBA 01/2019 - 02/2016
2	enzastaurinIBA 03/2012 - 03/2010
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 03/2009 - 02/2006
2	Imatinib Mesylate (Gleevec)FDA Link 10/2008 - 02/2006
2	Irinotecan (Camptosar)FDA LinkGeneric 09/2007 - 02/2006
2	Calmodulin-Binding Proteins (Caldesmon)IBA 06/2005 - 08/2003
1	alpha-hydroxyglutarateIBA 06/2024
1	Prednisolone (Predate)FDA LinkGeneric 01/2024
1	Immune Checkpoint InhibitorsIBA 02/2023
1	thiamine triphosphorate (TTP)IBA 01/2023
1	tyrosine receptor (receptor, tyrosine)IBA 01/2023
1	cyclo(Arg-Pro) (CI 4)IBA 01/2023
1	Clobazam (HR 376)IBA 01/2023
1	Phosphotransferases (Kinase)IBA 01/2023
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2023
1	Growth Factor ReceptorsIBA 01/2023
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2022
1	Everolimus FDA Link 12/2022
1	ceritinibIBA 01/2022
1	selinexorIBA 01/2022
1	Lacosamide FDA Link 08/2021

Therapy/Procedure

60	Drug Therapy (Chemotherapy) 06/2024 - 03/2003
60	Radiotherapy 12/2023 - 03/2003
35	Therapeutics 06/2024 - 05/2005
9	Chemoradiotherapy 01/2020 - 05/2008
6	Precision Medicine 10/2023 - 01/2010
6	Aftercare (After-Treatment) 05/2021 - 12/2007
4	Stem Cell Transplantation 12/2017 - 05/2005
3	Immunotherapy 10/2023 - 11/2014
2	Conformal Radiotherapy 12/2022 - 01/2021
2	Palliative Care (Palliative Therapy) 01/2021 - 12/2020
2	Adjuvant Chemotherapy 12/2014 - 12/2007
1	Time-to-Treatment 01/2023
1	Vocational Rehabilitation 12/2022